Michele Basso, Ph.D.

Michele Basso, Ph.D.

Faculty
Professor
mbasso@mednet.ucla.edu
Office: 

Department of Psychiatry 635 Charles Young Dr., Box 959573 Los Angeles, CA 90095-9753 (Campus Mail Code 957322)

(310) 825-9941

Research

Michele A. Basso is currently the director of the Fuster Laboratory of Cognitive Neuroscience at UCLA’s Semel Institute for Neuroscience and Human Behavior. The laboratory runs a research program focusing on basic questions of science that may have direct clinical impact on the treatment of certain diseases, including Parkinson’s disease. One of Dr. Basso’s current target research projects investigates the role of two parts of the brain, the basal ganglia and the superior colliculus, in saccadic (quick and simultaneous) eye movement decision-making. Saccadic eye movement choices, like many other action selections, are routed through the basal ganglia and superior colliculus within the brain. Further study of the link between these parts of the brain and saccadic eye movement selection may yield a better understanding of how Parkinson’s disease may cause decreases in patients’ decision-making ability.

Bibliography

Ghitani Nima, Bayguinov Peter O, Basso Michele A, Jackson Meyer B A sodium afterdepolarization in rat superior colliculus neurons and its contribution to population activity Journal of neurophysiology, 2016; 116(1): 191-200.

Perugini Alessandra, Ditterich Jochen, Basso Michele A Patients with Parkinson's Disease Show Impaired Use of Priors in Conditions of Sensory Uncertainty Current biology : CB, 2016; 26(14): 1902-10.

Basso Michele A Monkey neurophysiology to clinical neuroscience and back again Proceedings of the National Academy of Sciences of the United States of America, 2016; 113(24): 6591-3.

Crapse Trinity B, Basso Michele A Insights into decision making using choice probability Journal of neurophysiology, 2015; 114(6): 3039-49.

Grimaldi Piercesare, Lau Hakwan, Basso Michele A There are things that we know that we know, and there are things that we do not know we do not know: Confidence in decision-making Neuroscience and biobehavioral reviews, 2015; 55: 88-97.

Bayguinov Peter O, Ghitani Nima, Jackson Meyer B, Basso Michele A A hard-wired priority map in the superior colliculus shaped by asymmetric inhibitory circuitry Journal of neurophysiology, 2015; 114(1): 662-76.

Vokoun Corinne R, Huang Xin, Jackson Meyer B, Basso Michele A Response normalization in the superficial layers of the superior colliculus as a possible mechanism for saccadic averaging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(23): 7976-87.

Ghitani Nima, Bayguinov Peter O, Vokoun Corinne R, McMahon Shane, Jackson Meyer B, Basso Michele A Excitatory synaptic feedback from the motor layer to the sensory layers of the superior colliculus The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(20): 6822-33.

Mahamed Safraaz, Garrison Tiffany J, Shires Joel, Basso Michele A Stimulation of the Substantia Nigra Influences the Specification of Memory-Guided Saccades Journal of neurophysiology, 2013; 39(1): .

Powers Alice S, Basso Michele A, Evinger Craig Blinks slow memory-guided saccades Journal of neurophysiology, 2013; 109(3): 734-41.

Vokoun Corinne R, Jackson Meyer B, Basso Michele A Circuit dynamics of the superior colliculus revealed by in vitro voltage imaging Annals of the New York Academy of Sciences, 2011; 1233(2): 41-7.

Li Xiaobing, Basso Michele A Cues to move increased information in superior colliculus tuning curves Journal of neurophysiology, 2011; 106(2): 690-703.

Shires Joel, Joshi Siddhartha, Basso Michele A Shedding new light on the role of the basal ganglia-superior colliculus pathway in eye movements Current opinion in neurobiology, 2010; 20(6): 717-25.

Vokoun Corinne R, Jackson Meyer B, Basso Michele A Intralaminar and interlaminar activity within the rodent superior colliculus visualized with voltage imaging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(32): 10667-82.

Kim Byounghoon, Basso Michele A A probabilistic strategy for understanding action selection The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(6): 2340-55.

Gooding Diane C, Basso Michele A The tell-tale tasks: a review of saccadic research in psychiatric patient populations Brain and cognition, 2008; 68(3): 371-90.

Liu Ping, Basso Michele A Substantia nigra stimulation influences monkey superior colliculus neuronal activity bilaterally Journal of neurophysiology, 2008; 100(2): 1098-112.

Basso Michele A Electrical stimulation of nervous system tissue. Introduction Neuroscience and biobehavioral reviews, 2008; 32(3): 331.

Li Xiaobing, Basso Michele A Preparing to move increases the sensitivity of superior colliculus neurons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008; 28(17): 4561-77.

Kim Byounghoon, Basso Michele A Saccade target selection in the superior colliculus: a signal detection theory approach The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008; 28(12): 2991-3007.

Utter Amy A, Basso Michele A The basal ganglia: an overview of circuits and function Neuroscience and biobehavioral reviews, 2008; 32(3): 333-42.

Basso Michele A, Liu Ping Context-dependent effects of substantia nigra stimulation on eye movements Journal of neurophysiology, 2007; 97(6): 4129-42.

Smith Joshua J, Hadzic Vezira, Li Xiaobing, Liu Ping, Day Tiffany, Utter Amy, Kim Byounghoon, Washington Ida M, Basso Michele A Objective measures of health and well-being in laboratory rhesus monkeys (Macaca mulatta) Journal of medical primatology, 2006; 35(6): 388-96.

Li Xiaobing, Kim Byounghoon, Basso Michele A Transient pauses in delay-period activity of superior colliculus neurons Journal of neurophysiology, 2006; 95(4): 2252-64.

Li Xiaobing, Basso Michele A Competitive stimulus interactions within single response fields of superior colliculus neurons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005; 25(49): 11357-73.

Basso Michele A, Pokorny Jennifer J, Liu Ping Activity of substantia nigra pars reticulata neurons during smooth pursuit eye movements in monkeys The European journal of neuroscience, 2005; 22(2): 448-64.

Basso Michele A, Uhlrich Daniel, Bickford Martha E Cortical function: a view from the thalamus Neuron, 2005; 45(4): 485-8.

Williamson Shawn S, Zivotofsky Ari Z, Basso Michele A Modulation of gaze-evoked blinks depends primarily on extraretinal factors Journal of neurophysiology, 2005; 93(1): 627-32.

Basso Michele A, Wurtz Robert H Neuronal activity in substantia nigra pars reticulata during target selection The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002; 22(5): 1883-94.